BDBM32609 1-aza-2-oxobicyclo[5.3.0]decane scaffold, 36b

SMILES CC[C@H](NC)C(=O)N[C@H]1[C@@H](CNC(=O)c2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1

InChI Key InChIKey=OXPBXFHQSIRUSU-HVSNEVFASA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 32609   

TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Universita Degli Studi Di Milano

LigandPNGBDBM32609(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 36b)
Affinity DataIC50:  120nMAssay Description:Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Istituto Di Scienze E Tecnologie Molecolari (Istm)

Curated by ChEMBL
LigandPNGBDBM32609(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 36b)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of SMAC derived peptide abuRPF-K(5-Fam)-NH2 interaction with recombinant human C-terminal 6His-tagged cIAP1 BIR3 domain (245 to 357 residu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Universita Degli Studi Di Milano

LigandPNGBDBM32609(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 36b)
Affinity DataIC50:  55nMAssay Description:Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed