BDBM33110 5-[(6-Bromo-2-hydroxy-naphthalen-1-ylmethylene)-amino]-1,3-dihydro-benzoimidazol-2-one::5-[[(E)-(6-bromo-2-keto-1-naphthylidene)methyl]amino]-1,3-dihydrobenzimidazol-2-one::5-[[(Z)-(6-bromanyl-2-oxidanylidene-naphthalen-1-ylidene)methyl]amino]-1,3-dihydrobenzimidazol-2-one::5-[[(Z)-(6-bromo-2-keto-1-naphthylidene)methyl]amino]-1,3-dihydrobenzimidazol-2-one::5-[[(Z)-(6-bromo-2-oxo-1-naphthalenylidene)methyl]amino]-1,3-dihydrobenzimidazol-2-one::5-[[(Z)-(6-bromo-2-oxonaphthalen-1-ylidene)methyl]amino]-1,3-dihydrobenzimidazol-2-one::MLS000553451::SMR000171789::cid_5761516

SMILES Oc1ccc2cc(Br)ccc2c1C=Nc1ccc2[nH]c(=O)[nH]c2c1

InChI Key InChIKey=AQWGSBHYJQLIAU-UHFFFAOYSA-N

Data  3 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 33110   

TargetBcl-2-related protein A1(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33110(5-[(6-Bromo-2-hydroxy-naphthalen-1-ylmethylene)-am...)
Affinity DataEC50:  4.46E+3nMpH: 7.4 T: 2°CAssay Description:The multiplex is constructed by using beads for each protein target that have been labeled with varying intensities of red color, so that each assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM33110(5-[(6-Bromo-2-hydroxy-naphthalen-1-ylmethylene)-am...)
Affinity DataIC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:The purpose of this assay is to identify non-competititve inhibitors of human PMI. This is accomplished by using a G6PD- NADPH-coupled assay. In the ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33110(5-[(6-Bromo-2-hydroxy-naphthalen-1-ylmethylene)-am...)
Affinity DataEC50:  4.15E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEndoribonuclease toxin MazF(Escherichia coli str. K-12 substr. MG1655)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM33110(5-[(6-Bromo-2-hydroxy-naphthalen-1-ylmethylene)-am...)
Affinity DataEC50:  5.48E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGlycoprotein 42(Human herpesvirus 4 type 2)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM33110(5-[(6-Bromo-2-hydroxy-naphthalen-1-ylmethylene)-am...)
Affinity DataIC50:  2.68E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-related protein A1(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33110(5-[(6-Bromo-2-hydroxy-naphthalen-1-ylmethylene)-am...)
Affinity DataEC50:  1.35E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEndoribonuclease toxin MazF(Escherichia coli str. K-12 substr. MG1655)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM33110(5-[(6-Bromo-2-hydroxy-naphthalen-1-ylmethylene)-am...)
Affinity DataEC50: >9.90E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM33110(5-[(6-Bromo-2-hydroxy-naphthalen-1-ylmethylene)-am...)
Affinity DataIC50:  5.40E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay