BDBM342172 6-(4-fluorophenyl)-4-[4-[5-(4- fluorophenyl)-4H-1,2,4-triazol-3-yl]-1- piperidyl]-7H-pyrrolo[2,3-d]pyrimidine::US9771369, Compound P-3206

SMILES Fc1ccc(cc1)-c1cc2c(ncnc2[nH]1)N1CCC(CC1)c1nnc([nH]1)-c1ccc(F)cc1

InChI Key InChIKey=QAEBJNSATRRFQQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 342172   

TargetMast/stem cell growth factor receptor Kit [D816V](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM342172(6-(4-fluorophenyl)-4-[4-[5-(4- fluorophenyl)-4H-1,...)
Affinity DataKi:  500nMAssay Description:The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM342172(6-(4-fluorophenyl)-4-[4-[5-(4- fluorophenyl)-4H-1,...)
Affinity DataKi:  5.50E+3nMAssay Description:Assays for biochemical cell-based activity of c-kit kinase are known in the art, for example, as described in U.S. Pat. Nos. 7,498,342 and 7,846,941,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent