BDBM35491 Benzoic acid 5-amino-1-(4-methoxy-benzenesulfonyl)-1H-pyrazol-3-yl ester::MLS000033898::SMR000014915::[5-amino-1-(4-methoxyphenyl)sulfonylpyrazol-3-yl] benzoate::[5-azanyl-1-(4-methoxyphenyl)sulfonyl-pyrazol-3-yl] benzoate::benzoic acid [5-amino-1-(4-methoxyphenyl)sulfonyl-3-pyrazolyl] ester::benzoic acid [5-amino-1-(4-methoxyphenyl)sulfonyl-pyrazol-3-yl] ester::cid_655490

SMILES COc1ccc(cc1)S(=O)(=O)n1nc(OC(=O)c2ccccc2)cc1N

InChI Key InChIKey=FQICFDBMQBCJDT-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 35491   

TargetCathepsin B(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM35491(Benzoic acid 5-amino-1-(4-methoxy-benzenesulfonyl)...)
Affinity DataIC50:  9.56E+3nMpH: 6.8 T: 2°CAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCathepsin B(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM35491(Benzoic acid 5-amino-1-(4-methoxy-benzenesulfonyl)...)
Affinity DataIC50:  9.56E+3nMAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCathepsin G(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM35491(Benzoic acid 5-amino-1-(4-methoxy-benzenesulfonyl)...)
Affinity DataIC50:  2.08E+4nMAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGenome polyprotein(West Nile virus)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35491(Benzoic acid 5-amino-1-(4-methoxy-benzenesulfonyl)...)
Affinity DataIC50:  105nMAssay Description:The HTS assay to identify Inhibitors of West Nile Virus (WNV) NS2bNS3 Proteinase was proposed by Dr Alex Strongin of the Burnham Institute XO1-MH0776...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGenome polyprotein(West Nile virus)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35491(Benzoic acid 5-amino-1-(4-methoxy-benzenesulfonyl)...)
Affinity DataIC50:  105nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-5(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM35491(Benzoic acid 5-amino-1-(4-methoxy-benzenesulfonyl)...)
Affinity DataIC50:  2.54E+3nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGenome polyprotein(West Nile virus)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35491(Benzoic acid 5-amino-1-(4-methoxy-benzenesulfonyl)...)
Affinity DataIC50:  105nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 3(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM35491(Benzoic acid 5-amino-1-(4-methoxy-benzenesulfonyl)...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of N-terminal His6-tagged Zika virus NS2B (45 to 96 residues) - NS3 (1 to 177 residues) protease domain expressed in Escherichia coli BL21...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM35491(Benzoic acid 5-amino-1-(4-methoxy-benzenesulfonyl)...)
Affinity DataIC50: >5.00E+4nMAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay