BDBM36903 1-[(2,4-dimethoxyphenyl)-(4-morpholinyl)methyl]-2-naphthalenol::1-[(2,4-dimethoxyphenyl)-morpholin-4-yl-methyl]naphthalen-2-ol::1-[(2,4-dimethoxyphenyl)-morpholin-4-ylmethyl]naphthalen-2-ol::1-[(2,4-dimethoxyphenyl)-morpholino-methyl]-2-naphthol::MLS000039063::SMR000035686::cid_621551

SMILES COc1ccc(C(N2CCOCC2)c2c(O)ccc3ccccc23)c(OC)c1

InChI Key InChIKey=MCQQTDAWUXZMTO-UHFFFAOYSA-N

Data  1 IC50  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 36903   

TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36903(1-[(2,4-dimethoxyphenyl)-(4-morpholinyl)methyl]-2-...)
Affinity DataEC50:  3.84E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36903(1-[(2,4-dimethoxyphenyl)-(4-morpholinyl)methyl]-2-...)
Affinity DataEC50:  1.45E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36903(1-[(2,4-dimethoxyphenyl)-(4-morpholinyl)methyl]-2-...)
Affinity DataEC50:  4.94E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM36903(1-[(2,4-dimethoxyphenyl)-(4-morpholinyl)methyl]-2-...)
Affinity DataIC50:  1.62E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM36903(1-[(2,4-dimethoxyphenyl)-(4-morpholinyl)methyl]-2-...)
Affinity DataEC50:  1.25E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
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TargetSerine/threonine-protein phosphatase(Yeast)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM36903(1-[(2,4-dimethoxyphenyl)-(4-morpholinyl)methyl]-2-...)
Affinity DataEC50:  1.80E+5nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, calcineurin, stress response Assay Overview: Method for determining if compound acts as Ca...More data for this Ligand-Target Pair
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TargetATP-dependent molecular chaperone HSP82(Yeast)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM36903(1-[(2,4-dimethoxyphenyl)-(4-morpholinyl)methyl]-2-...)
Affinity DataEC50: >1.60E+5nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, stress response Assay Overview: Method for determining if compound acts as Hsp90 inh...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetATP-dependent molecular chaperone HSP82(Yeast)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM36903(1-[(2,4-dimethoxyphenyl)-(4-morpholinyl)methyl]-2-...)
Affinity DataEC50:  2.85E+3nMAssay Description:Broad Institute: Reversing Antifungal Drug Resistance Project ID: 2037 Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, Calcineurin, ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetATP-dependent molecular chaperone HSP82(Yeast)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM36903(1-[(2,4-dimethoxyphenyl)-(4-morpholinyl)methyl]-2-...)
Affinity DataEC50: >1.60E+5nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, Calcineurin, stress response Primary Collaborators: Susan Lindquist, Whitehead Insti...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay