BDBM387027 (2S)-2-methoxy-N-[5-[[(3R)-1-(6-methylpyridazin-3-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]-2-phenyl-acetamide::US9938265, Example 14

SMILES CO[C@H](C(=O)Nc1nnc(N[C@@H]2CCN(C2)c2ccc(C)nn2)s1)c1ccccc1

InChI Key InChIKey=GZUNLBJLISQWRR-WBVHZDCISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 387027   

TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM387027((2S)-2-methoxy-N-[5-[[(3R)-1-(6-methylpyridazin-3-...)
Affinity DataIC50:  44.3nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent