Compile Data Set for Download or QSAR
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Found 110 Enz. Inhib. hit(s) with Target = 'Glutaminase kidney isoform, mitochondrial [63-669]'
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416666((2S)-2-Methoxy-2-[3-methoxy-5-(trifluoromethoxy)ph...)
Affinity DataIC50:  6.11nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416667((2R)-2-Methoxy-2-[3-methoxy-5-(trifluoromethoxy)ph...)
Affinity DataIC50:  6.35nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM387023((2S)-N-[5-[[(3R)-1-(5-chloropyridazin-3-yl)pyrroli...)
Affinity DataIC50:  15.9nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM387034(N-[5-[[(3R)-1-(6-fluoropyridazin-3-yl)pyrrolidin-3...)
Affinity DataIC50:  18.9nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416687((2R)-2-(3,5-Dimethoxyphenyl)-2-methoxy-N-[5-[[(3R)...)
Affinity DataIC50:  20nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416687((2R)-2-(3,5-Dimethoxyphenyl)-2-methoxy-N-[5-[[(3R)...)
Affinity DataIC50:  20nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416638((2S)-2-[3-(3-Fluoroazetidin-1-yl)phenyl]-2-methoxy...)
Affinity DataIC50:  20.6nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416681((2R)-2-Methoxy-2-[3-(oxetan-3-yl)phenyl]-N-[5-[[(3...)
Affinity DataIC50:  22.6nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM387019((2S)-2-[3-(difluoromethoxy)phenyl]-N-[5-[[(3R)-1-(...)
Affinity DataIC50:  22.7nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM492979(2-(3,5-dimethoxyphenyl)-N-[5-[[(3R)-1-(6-fluoropyr...)
Affinity DataIC50:  23.5nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM387030(N-[5-[[(3R)-1-(6-fluoropyridazin-3-yl)pyrrolidin-3...)
Affinity DataIC50:  24.3nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416677((2R)-2-(3,5-Dimethoxyphenyl)-2-methoxy-N-[5-[[(3R)...)
Affinity DataIC50:  25.2nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416654((2S)-2-(3,5-Dimethoxyphenyl)-2-ethoxy-N-[5-[[(3R)-...)
Affinity DataIC50:  28nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416652((2R)-3-Methoxy-2-(3-methoxyphenyl)-N-[5-[[(3R)-1-p...)
Affinity DataIC50:  28.8nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM387007((2S)-N-[5-[[(3R)-1-(6-Fluoropyridazin-3-yl)pyrroli...)
Affinity DataIC50:  30.3nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416643((2S)-2-Methoxy-2-[3-(3-methoxyazetidin-1-yl)phenyl...)
Affinity DataIC50:  30.8nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM387021((2S)-2-(4-Fluorophenyl)-2-methoxy-N-[5-[[(3R)-1-(5...)
Affinity DataIC50:  31.1nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416664((2S)-2-[3-(3-Fluoroazetidin-1-yl)-5-methoxy-phenyl...)
Affinity DataIC50:  34.9nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM387045((2S)-N-[5-[[(3R)-1-(5-chloropyridazin-3-yl)pyrroli...)
Affinity DataIC50:  35.3nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM387025((2S)-N-[5-[[(3R)-1-(5-Chloropyridazin-3-yl)pyrroli...)
Affinity DataIC50:  35.3nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM387008((2S)-N-[5-[[(3R)-1-(6-Fluoropyridazin-3-yl)pyrroli...)
Affinity DataIC50:  38.8nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416683((2R)-2-Ethoxy-N-[5-[[(3R)-1-pyridazin-3-ylpyrrolid...)
Affinity DataIC50:  40.1nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416650((2S)-2-(3,5-Dimethoxyphenyl)-2-methoxy-N-[5-[[(3R)...)
Affinity DataIC50:  42.3nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416669((2R)-2-Methoxy-2-[3-(3-methoxyazetidin-1-yl)phenyl...)
Affinity DataIC50:  43.8nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM387027((2S)-2-methoxy-N-[5-[[(3R)-1-(6-methylpyridazin-3-...)
Affinity DataIC50:  44.3nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM492996(2-[3-(3,3-difluoroazetidin-1-yl)phenyl]-N-[5-[[(3R...)
Affinity DataIC50:  46.7nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416686((2S)-2-(3,5-Dimethoxyphenyl)-2-methoxy-N-[5-[[(3R)...)
Affinity DataIC50:  48.2nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416686((2S)-2-(3,5-Dimethoxyphenyl)-2-methoxy-N-[5-[[(3R)...)
Affinity DataIC50:  48.2nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416686((2S)-2-(3,5-Dimethoxyphenyl)-2-methoxy-N-[5-[[(3R)...)
Affinity DataIC50:  48.2nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416679((2R)-[3-(Difluoromethoxy)phenyl]-2-ethoxy-N-[5-[[(...)
Affinity DataIC50:  50.4nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM492982(2-[3-(3,3-difluoroazetidin-1-yl)phenyl]-2-ethoxy-N...)
Affinity DataIC50:  51.1nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416680((2S)-2-Methoxy-2-[3-(oxetan-3-yl)phenyl]-N-[5-[[(3...)
Affinity DataIC50:  52.6nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM387005((2S)-2-Methoxy-2-(3-methoxyphenyl)-N-[5-[[(3R)-1-(...)
Affinity DataIC50:  55.4nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM387032(2-(4-fluorophenyl)-N-[5-[[(3R)-1-(6-fluoropyridazi...)
Affinity DataIC50:  55.7nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416663((2R)-N-[5-[[(3R)-1-(6-Fluoropyridazin-3-yl)pyrroli...)
Affinity DataIC50:  59.1nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM387026((2S)-2-Methoxy-N-[5-[[(3R)-1-(5-methylpyridazin-3-...)
Affinity DataIC50:  59.2nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM387044((2S)-2-methoxy-N-[5-[[(3R)-1-(5-methylpyridazin-3-...)
Affinity DataIC50:  59.2nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416651((2R)-2-(3,5-Dimethoxyphenyl)-2-methoxy-N-[5-[[(3R)...)
Affinity DataIC50:  59.6nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416684((2S)-2-[4-Fluoro-3-(trifluoromethoxy)phenyl]-2-met...)
Affinity DataIC50:  64.1nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416657((2S)-2-[4-Fluoro-3-(3-fluoroazetidin-1-yl)phenyl]-...)
Affinity DataIC50:  64.9nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM387030(N-[5-[[(3R)-1-(6-fluoropyridazin-3-yl)pyrrolidin-3...)
Affinity DataIC50:  65.3nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416688((2S)-2-ethoxy-2-[3-(3-methoxyazetidin-1-yl)phenyl]...)
Affinity DataIC50:  68.5nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416689((2R)-2-ethoxy-2-[3-(3-methoxyazetidin-1-yl)phenyl]...)
Affinity DataIC50:  68.5nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416685((2R)-2-[4-Fluoro-3-(trifluoromethoxy)phenyl]-2-met...)
Affinity DataIC50:  69.3nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM387036(2-(4-fluoro-3-methoxy-phenyl)-N-[5-[[(3R)-1-(6-flu...)
Affinity DataIC50:  71.3nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416644((2R)-2-Methoxy-2-[3-(3-methoxyazetidin-1-yl)phenyl...)
Affinity DataIC50:  72.1nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM492944((2S)-2-[3-(3-Fluoroazetidin-1-yl)-5-methoxy-phenyl...)
Affinity DataIC50:  72.2nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416639((2R)-2-[3-(3-Fluoroazetidin-1-yl)phenyl]-2-methoxy...)
Affinity DataIC50:  72.6nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM416671((2R)-2-Methoxy-2-[3-(3-methoxyazetidin-1-yl)phenyl...)
Affinity DataIC50:  75.1nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial [63-669](Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM492990(2-[3-(3-fluoroazetidin-1-yl)phenyl]-2-methoxy-N-[5...)
Affinity DataIC50:  77nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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