BDBM397293 US10596172, Compound I-11::US10828300, Compound I-11::US11351168, Compound I-11::US9987276, Compound I-11
SMILES Cc1cnc(Nc2cccc(c2)S(N)(=O)=O)nc1Nc1ccc2CN(CCc2c1)C(=O)CCl
InChI Key InChIKey=PLUJQIOUOXACEJ-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 397293
Affinity DataIC50: <10nMAssay Description:EGFR (WT) and EGFR (T790M/L858R): The Omnia Assay Protocol for potency assessment against EGFR is performed as described in Example 251 above except ...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:EGFR (WT) and EGFR (T790M/L858R): The Omnia Assay Protocol for potency assessment against EGFR is performed as described in Example 251 above except ...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:JAK3: The Omnia Assay Protocol for potency assessment against JAK3 was performed in a substantially similar manner as that described in Example 251 a...More data for this Ligand-Target Pair