BDBM403445 (6S,9R)- or (6R,9S)- 4-(1- (difluoromethyl)- 1H-pyrazol-4-yl)- 6,7,8,9-tetrahydro- 5H-6,9-epoxycyclo- hepta[b]pyridine-2- carboxamide::US10335399, Example 1-5B::US10806724, Example 1-5B

SMILES NC(=O)c1cc(-c2cnn(c2)C(F)F)c2C[C@@H]3CC[C@@H](O3)c2n1

InChI Key InChIKey=KITCKKYBIDIUCD-QPUJVOFHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 403445   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM403445((6S,9R)- or (6R,9S)- 4-(1- (difluoromethyl)- 1H-py...)
Affinity DataIC50:  326nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent