BDBM4304 (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-2-enamide::CHEMBL56731::cid_5328771::tyrphostin 1
SMILES Oc1ccc(\C=C(/C#N)C(=O)Nc2ccccc2)cc1O
InChI Key InChIKey=HKHOVJYOELRGMV-XYOKQWHBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 4304
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Hebrew University of Jerusalem
Hebrew University of Jerusalem
Affinity DataIC50: 1.00E+4nMAssay Description:The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...More data for this Ligand-Target Pair