BDBM436174 US10590109, Compound 1
SMILES FC(F)(F)c1cccc(c1)C(=O)Nc1cccc(Oc2ccc3nccnc3c2)c1
InChI Key InChIKey=OLADGUMEIVQDEE-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 436174
TargetFibroblast growth factor receptor 4 [460-802](Homo sapiens (Human))
Nanjing Innocare Pharma Tech
US Patent
Nanjing Innocare Pharma Tech
US Patent
Affinity DataIC50: <10nMAssay Description:FGFR4:The in vitro activity of FGFR4 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HTR...More data for this Ligand-Target Pair
Affinity DataIC50: >100nMAssay Description:Inhibitory activities of compounds against KDR (VEGFR2) were also measured by Invitrogen using Z'-LYTE Method as described above with the following m...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Inhibitory activities Inhibitory activities of compounds against BRAF, and BRAF V600E were measured by Invitrogen using Z′-LYTEŽ Method as brie...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1 [308-731](Homo sapiens (Human))
Nanjing Innocare Pharma Tech
US Patent
Nanjing Innocare Pharma Tech
US Patent
Affinity DataIC50: >1.00E+3nMAssay Description:FGFR1: The in vitro activity of FGFR1 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HT...More data for this Ligand-Target Pair