BDBM445132 (2S,4S)-1-Cyano-4-methoxy-N-methyl-N-(4-phenylthiazol-2-yl)pyrrolidine-2-carboxamide::US10669234, Example 71::US11319287, Example 71

SMILES CO[C@H]1C[C@H](N(C1)C(=O)OC(C)(C)C)C(=O)N(C)c1nc(cs1)-c1ccccc1

InChI Key InChIKey=KNMIHEMZRYEGMW-RDJZCZTQSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445132   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Mission Therapeutics

US Patent
LigandPNGBDBM445132((2S,4S)-1-Cyano-4-methoxy-N-methyl-N-(4-phenylthia...)
Affinity DataIC50:  550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Mission Therapeutics

US Patent
LigandPNGBDBM445132((2S,4S)-1-Cyano-4-methoxy-N-methyl-N-(4-phenylthia...)
Affinity DataIC50:  550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent