BDBM447667 3-(3-methoxy-3-methylazetidin-1-yl)-6-((3-methoxy-4-((6-methyl-pyridin-3-yl)methoxy)phenyl)amino)quinoxaline-5-carbonitrile::US10689362, Example 138
SMILES COc1cc(Nc2ccc3ncc(nc3c2C#N)N2CC(C)(C2)OC)ccc1OCc1ccc(C)nc1
InChI Key InChIKey=MHQSGLRFCSEFMI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 447667
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Development Center For Biotechnology
US Patent
Development Center For Biotechnology
US Patent
Affinity DataKi: 27.5nMAssay Description:c-KIT: Inhibition of c-KIT kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditions were 20 ...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Development Center For Biotechnology
US Patent
Development Center For Biotechnology
US Patent
Affinity DataIC50: >1.00E+6nMAssay Description:PDGFRβ: Inhibition of PDGFRβ kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditi...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Development Center For Biotechnology
US Patent
Development Center For Biotechnology
US Patent
Affinity DataIC50: >1.00E+6nMAssay Description:FLT3: Inhibition of FLT3 kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditions were 5 ng ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Development Center For Biotechnology
US Patent
Development Center For Biotechnology
US Patent
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair