BDBM458842 US10759792, Compound I-11::US11325908, Compound I-11
SMILES Cc1ccc2c(c1)[nH]c1nccc(-c3cccc(NCCN)c3)c21
InChI Key InChIKey=PPOHGJJUQFCJFC-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 458842
TargetCalcium/calmodulin-dependent protein kinase type II subunit gamma(Homo sapiens (Human))
The Johns Hopkins University
US Patent
The Johns Hopkins University
US Patent
Affinity DataIC50: <100nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Homo sapiens (Human))
The Johns Hopkins University
US Patent
The Johns Hopkins University
US Patent
Affinity DataIC50: <50nMAssay Description:Compounds were added in 5 uL volume to wells in UV transparent 96-well plates (½ area well size). The final compound concentrations tested ranged fro...More data for this Ligand-Target Pair