BDBM463444 US10781182, Compound IA2-121::US11091445, Compound code IA2-121
SMILES CCOc1nc2cc(Cl)c(OC)cc2n1CCNC(C)=O
InChI Key InChIKey=LRRDNGSYVNSAEO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 463444
Affinity DataKi: 0.880nMAssay Description:Displacement of 2-[1251]-iodomelatonin from human MT1 receptor expressed in CHO cells incubated for 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.930nMAssay Description:Displacement of 2-[1251]-iodomelatonin from human MT2 receptor expressed in CHO cells incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 0.140nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as increase in cAMP levels incubated at 28 degreeC by cellular dielectric spec...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0350nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as increase in forskolin induced cAMP production incubated at 37 degreeC by Hi...More data for this Ligand-Target Pair
Affinity DataEC50: 0.270nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as increase in cAMP production incubated at 37 degreeC by fluorometric methodMore data for this Ligand-Target Pair