BDBM474288 2-((3-(difluoromethoxy)pyridin-2-yl)methyI)-8- (imidazo[1,2-a]pyridin-6-yl)-7-(oxazol-2-yl)-[ 1,2, 4]triazolo[1,5-c]pyrimidin-5-amine::US10858365, Compound 74
SMILES Nc1nc(-c2ncco2)c(-c2ccc3nncn3c2)c2nc(Cc3ncccc3OC(F)F)nn12
InChI Key InChIKey=QYOQJRWDIJNFKL-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 474288
Affinity DataIC50: 0.800nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair