BDBM481128 US10906896, Cpd 809::US11725005, Compound 809

SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cncc(c3)-c3oncc3C)c2)CC1

InChI Key InChIKey=ADGOPPKEIZXKAZ-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 481128   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Inhibikase Therapeutics

US Patent
LigandPNGBDBM481128(US10906896, Cpd 809 | US11725005, Compound 809)
Affinity DataKi:  7.80nMAssay Description:Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Inhibikase Therapeutics

US Patent
LigandPNGBDBM481128(US10906896, Cpd 809 | US11725005, Compound 809)
Affinity DataIC50:  77nMAssay Description:Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Inhibikase Therapeutics

US Patent
LigandPNGBDBM481128(US10906896, Cpd 809 | US11725005, Compound 809)
Affinity DataIC50:  7.80nMAssay Description:Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl22 mM DTT) and Stop buffer (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Reag...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Inhibikase Therapeutics

US Patent
LigandPNGBDBM481128(US10906896, Cpd 809 | US11725005, Compound 809)
Affinity DataIC50:  47nMAssay Description:Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl22 mM DTT) and Stop buffer (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Reag...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Inhibikase Therapeutics

US Patent
LigandPNGBDBM481128(US10906896, Cpd 809 | US11725005, Compound 809)
Affinity DataIC50:  77nMAssay Description:Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl22 mM DTT) and Stop buffer (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Reag...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Inhibikase Therapeutics

US Patent
LigandPNGBDBM481128(US10906896, Cpd 809 | US11725005, Compound 809)
Affinity DataIC50:  47nMAssay Description:Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re...More data for this Ligand-Target Pair
In DepthDetails US Patent