BDBM490314 US10968215, Compound 191::US10968215, Compound 202

SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1cc2c(ccn2c(N(C)C2CCN(CC(F)(F)F)CC2)c1C)-c1ccn[nH]1

InChI Key InChIKey=ATRIQDOGGDRZLY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 490314   

LigandPNGBDBM490314(US10968215, Compound 191 | US10968215, Compound 20...)
Affinity DataIC50: <100nMAssay Description:EZH2Y641F: PRC2 complex experimental method: Experimental method: PRC2 complex (EZH2 Y641F/EED/SUZ12/RbAp48/AEBP2), H3(1-50) me1 substrate, methyl do...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM490314(US10968215, Compound 191 | US10968215, Compound 20...)
Affinity DataIC50: <100nMAssay Description:EZH2Y641F: PRC2 complex experimental method: Experimental method: PRC2 complex (EZH2 Y641F/EED/SUZ12/RbAp48/AEBP2), H3(1-50) me1 substrate, methyl do...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent