BDBM490316 US10968215, Compound 193::US10968215, Compound 204

SMILES CCN(C1CCN(CC(F)(F)F)CC1)c1c(C)c(cc2c(ncn12)-c1ccnc(c1)N(C)C)C(=O)NCc1c(OC)cc(C)[nH]c1=O

InChI Key InChIKey=GCUYZRJYMGHXJY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 490316   

LigandPNGBDBM490316(US10968215, Compound 193 | US10968215, Compound 20...)
Affinity DataIC50: <100nMAssay Description:EZH2Y641F: PRC2 complex experimental method: Experimental method: PRC2 complex (EZH2 Y641F/EED/SUZ12/RbAp48/AEBP2), H3(1-50) me1 substrate, methyl do...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM490316(US10968215, Compound 193 | US10968215, Compound 20...)
Affinity DataIC50: <100nMAssay Description:EZH2Y641F: PRC2 complex experimental method: Experimental method: PRC2 complex (EZH2 Y641F/EED/SUZ12/RbAp48/AEBP2), H3(1-50) me1 substrate, methyl do...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent