BDBM49484 (4-methoxyphenyl)-(4-phenylthiazol-2-yl)amine::MLS000565006::N-(4-methoxyphenyl)-4-phenyl-1,3-thiazol-2-amine::N-(4-methoxyphenyl)-4-phenyl-2-thiazolamine::SMR000152166::cid_1548457

SMILES COc1ccc(Nc2nc(cs2)-c2ccccc2)cc1

InChI Key InChIKey=NAVZSNBQDOGYKD-UHFFFAOYSA-N

Data  4 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 49484   

TargetTranscription factor p65(Homo sapiens (Human))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM49484((4-methoxyphenyl)-(4-phenylthiazol-2-yl)amine | ML...)
Affinity DataEC50:  752nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49484((4-methoxyphenyl)-(4-phenylthiazol-2-yl)amine | ML...)
Affinity DataIC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNuclear hormone receptor family member daf-12(Caenorhabditis elegans)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49484((4-methoxyphenyl)-(4-phenylthiazol-2-yl)amine | ML...)
Affinity DataEC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM49484((4-methoxyphenyl)-(4-phenylthiazol-2-yl)amine | ML...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of 5-lipoxygenase in human PMNL using arachidonic acid as substrate preincubated for 15 mins before substrate addition measured after 10 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49484((4-methoxyphenyl)-(4-phenylthiazol-2-yl)amine | ML...)
Affinity DataEC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM49484((4-methoxyphenyl)-(4-phenylthiazol-2-yl)amine | ML...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of partially purified recombinant 5-lipoxygenase (unknown origin) using arachidonic acid as substrate preincubated for 15 mins before subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear hormone receptor family member daf-12(Caenorhabditis elegans)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49484((4-methoxyphenyl)-(4-phenylthiazol-2-yl)amine | ML...)
Affinity DataIC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay