BDBM50014161 CHEMBL3260858::US11491146, Compound 5

SMILES OC(=O)[C@H](NC(=O)c1cccc(=S)n1O)c1ccccc1

InChI Key InChIKey=MUTGTTZIVAJIJK-GFCCVEGCSA-N

Data  2 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50014161   

TargetD-alanyl-D-alanine dipeptidase(Enterococcus faecium)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014161(CHEMBL3260858 | US11491146, Compound 5)
Affinity DataKi:  2.74E+3nMAssay Description:Inhibition of Enterococcus faecium VanX expressed in Escherichia coli BL21 (DE3) cells using D-alanyl-alpha-R-phenylthioglycine as substrate by color...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Individual

US Patent
LigandPNGBDBM50014161(CHEMBL3260858 | US11491146, Compound 5)
Affinity DataKi:  7.50E+3nMAssay Description:To identify potential MBL inhibitors, the relative change in the formation of hydrolyzed nitrocefin between treated and untreated VIM2 was determined...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014161(CHEMBL3260858 | US11491146, Compound 5)
Affinity DataIC50:  9.30E+4nMAssay Description:Inhibition of HDAC1 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014161(CHEMBL3260858 | US11491146, Compound 5)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Individual

US Patent
LigandPNGBDBM50014161(CHEMBL3260858 | US11491146, Compound 5)
Affinity DataIC50:  6.79E+4nMAssay Description:To identify potential MBL inhibitors, the relative change in the formation of hydrolyzed nitrocefin between treated and untreated VIM2 was determined...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014161(CHEMBL3260858 | US11491146, Compound 5)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014161(CHEMBL3260858 | US11491146, Compound 5)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of HDAC5 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014161(CHEMBL3260858 | US11491146, Compound 5)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of HDAC7 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014161(CHEMBL3260858 | US11491146, Compound 5)
Affinity DataIC50:  9.50E+4nMAssay Description:Inhibition of HDAC2 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014161(CHEMBL3260858 | US11491146, Compound 5)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of HDAC9 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014161(CHEMBL3260858 | US11491146, Compound 5)
Affinity DataIC50:  6.40E+4nMAssay Description:Inhibition of HDAC4 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed