BDBM50029495 7-Benzoylamino-4-methyl-9-oxo-4,9-dihydro-pyrazolo[5,1-b]quinazoline-2-carboxylic acid::CHEMBL137953

SMILES Cn1c2cc(nn2c(=O)c2cc(NC(=O)c3ccccc3)ccc12)C(O)=O

InChI Key InChIKey=IAZAGXDMMVWYKF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50029495   

TargetTumor necrosis factor receptor superfamily member 16(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50029495(7-Benzoylamino-4-methyl-9-oxo-4,9-dihydro-pyrazolo...)
Affinity DataIC50:  200nMAssay Description:Inhibition of [125I]- NGF binding to extracellular domain of p75 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 16(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50029495(7-Benzoylamino-4-methyl-9-oxo-4,9-dihydro-pyrazolo...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of mouse NGF binding to p75 (unknown origin) by SPR methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029495(7-Benzoylamino-4-methyl-9-oxo-4,9-dihydro-pyrazolo...)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of mouse NGF binding to TrkA (unknown origin) by SPR methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed