BDBM50029769 6-[2-(2,5-Dimethoxy-phenyl)-ethyl]-5-methyl-thieno[2,3-d]pyrimidine-2,4-diamine::CHEMBL322585

SMILES COc1ccc(OC)c(CCc2sc3nc(N)nc(N)c3c2C)c1

InChI Key InChIKey=CORRFHRBZLKMLF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50029769   

TargetDihydrofolate reductase(Pneumocystis carinii)
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50029769(6-[2-(2,5-Dimethoxy-phenyl)-ethyl]-5-methyl-thieno...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity was determined against dihydrofolate reductase in Pneumocystis carinii .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50029769(6-[2-(2,5-Dimethoxy-phenyl)-ethyl]-5-methyl-thieno...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of dihydrofolate reductase in pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50029769(6-[2-(2,5-Dimethoxy-phenyl)-ethyl]-5-methyl-thieno...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of dihydrofolate reductase in pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50029769(6-[2-(2,5-Dimethoxy-phenyl)-ethyl]-5-methyl-thieno...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50029769(6-[2-(2,5-Dimethoxy-phenyl)-ethyl]-5-methyl-thieno...)
Affinity DataIC50: >1.00E+4nMAssay Description:Tested for inhibitory activity against dihydrofolate reductase in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed