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Found 5 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50029769'
TargetDihydrofolate reductase(Pneumocystis carinii)
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50029769(6-[2-(2,5-Dimethoxy-phenyl)-ethyl]-5-methyl-thieno...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity was determined against dihydrofolate reductase in Pneumocystis carinii .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50029769(6-[2-(2,5-Dimethoxy-phenyl)-ethyl]-5-methyl-thieno...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of dihydrofolate reductase in pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50029769(6-[2-(2,5-Dimethoxy-phenyl)-ethyl]-5-methyl-thieno...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of dihydrofolate reductase in pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50029769(6-[2-(2,5-Dimethoxy-phenyl)-ethyl]-5-methyl-thieno...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50029769(6-[2-(2,5-Dimethoxy-phenyl)-ethyl]-5-methyl-thieno...)
Affinity DataIC50: >1.00E+4nMAssay Description:Tested for inhibitory activity against dihydrofolate reductase in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed