BDBM50029816 5-Chloro-pyridine-2-carboxylic acid (2-amino-ethyl)-amide::CHEMBL279390::Lazabemide::Ro-19-6327
SMILES NCCNC(=O)c1ccc(Cl)cn1
InChI Key InChIKey=JZXRLKWWVNUZRB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50029816
Affinity DataKi: 3.90nMAssay Description:Inhibition of human recombinant soluble MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 mins b...More data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Inhibition of human recombinant microsomal MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 min...More data for this Ligand-Target Pair
Affinity DataEC50: 7.10E+3nMAssay Description:Inhibition of human recombinant soluble MAO-B assessed as thermal shift after 20 mins by SYPRO orange staining-based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKd: 66nMAssay Description:Binding affinity to human recombinant microsomal MAO-B by ITCMore data for this Ligand-Target Pair