BDBM50029816 5-Chloro-pyridine-2-carboxylic acid (2-amino-ethyl)-amide::CHEMBL279390::Lazabemide::Ro-19-6327

SMILES NCCNC(=O)c1ccc(Cl)cn1

InChI Key InChIKey=JZXRLKWWVNUZRB-UHFFFAOYSA-N

Data  5 KI  24 IC50  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50029816   

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50029816(5-Chloro-pyridine-2-carboxylic acid (2-amino-ethyl...)
Affinity DataIC50:  120nMAssay Description:Inhibition of recombinant human MAO-B using benzylamine as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50029816(5-Chloro-pyridine-2-carboxylic acid (2-amino-ethyl...)
Affinity DataIC50:  37nMAssay Description:Inhibition of recombinant human MAO-B using benzylamine as substrate incubated for 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50029816(5-Chloro-pyridine-2-carboxylic acid (2-amino-ethyl...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human recombinant MAOB using benzylamine as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50029816(5-Chloro-pyridine-2-carboxylic acid (2-amino-ethyl...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI insect cells using benzylamine as substrate after 30 mins by spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed