BDBM50030196 CHEMBL3354065

SMILES CCCCC1CCN(CCCN2C(=O)CCc3ccccc23)CC1

InChI Key InChIKey=PHMGZAICAOYEAF-UHFFFAOYSA-N

Data  19 KI  9 IC50  8 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50030196   

TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030196(CHEMBL3354065)
Affinity DataIC50:  174nMAssay Description:Antagonist activity at human M1 receptor expressed in HEK293T cells assessed as inhibition of carbachol-induced response by BRET based beta-arrestin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030196(CHEMBL3354065)
Affinity DataIC50:  6nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D4 receptor expressed in HEK293 cell membranes after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030196(CHEMBL3354065)
Affinity DataIC50:  117nMAssay Description:Agonist activity at human SP/Myc epitope-tagged muscarinic M1 receptor expressed in HEK293T cells assessed as RLuc8-fused Galphaq activation after 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030196(CHEMBL3354065)
Affinity DataIC50:  2.24E+3nMAssay Description:Antagonist activity at human M4 receptor expressed in HEK293T cells assessed as inhibition of carbachol-induced response by BRET based Gq protein eng...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030196(CHEMBL3354065)
Affinity DataIC50:  7.59E+3nMAssay Description:Antagonist activity at human M4 receptor expressed in HEK293T cells assessed as inhibition of xanomeline-induced response by beta-arrestin engagement...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030196(CHEMBL3354065)
Affinity DataIC50:  178nMAssay Description:Antagonist activity at human M4 receptor expressed in HEK293T cells assessed as inhibition of carbachol-induced response by beta-arrestin engagement ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030196(CHEMBL3354065)
Affinity DataIC50:  4.79E+4nMAssay Description:Antagonist activity at human M4 receptor expressed in HEK293T cells assessed as inhibition of carbachol-induced response by BRET based Gq protein act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030196(CHEMBL3354065)
Affinity DataIC50:  1.59E+3nMAssay Description:Antagonist activity at human M1 receptor expressed in HEK293T cells assessed as inhibition of xanomeline-induced response by BRET based beta-arrestin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030196(CHEMBL3354065)
Affinity DataIC50:  1.20E+5nMAssay Description:Antagonist activity at human M4 receptor expressed in HEK293T cells assessed as inhibition of xanomeline-induced response by BRET based Gq protein en...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed