BDBM50056891 2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydrazide::2-hydroxybenzoic acid 2-(2-hydroxybenzoyl)hydrazide::CHEMBL36303::cid_65303

SMILES Oc1ccccc1C(=O)NNC(=O)c1ccccc1O

InChI Key InChIKey=UORSDGBOJHYJLV-UHFFFAOYSA-N

Data  19 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50056891   

TargetAlbumin(Bos taurus)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50056891(2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...)
Affinity DataIC50: >9.39E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50056891(2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of recombinant HIV1 integrase-mediated 3'-processing activity in presence of manganeseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056891(2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...)
Affinity DataIC50:  2.07E+3nMAssay Description:Inhibition of HIV-1 integrase enzyme by 3'-processing methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056891(2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...)
Affinity DataIC50:  730nMAssay Description:Inhibition of HIV-1 integrase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056891(2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...)
Affinity DataIC50:  730nMAssay Description:Inhibitory concentration as 50% inhibition of HIV-1 integrase enzyme at strand transfer stage of DNA integration.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056891(2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...)
Affinity DataIC50:  2.07E+3nMAssay Description:Inhibition of HIV-1 integrase enzyme at 3`- processing stage of DNA integrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056891(2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mg+2, and drug for 30 min followed by DNA for 1h) in strand transfer of preassembleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056891(2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mg+2, and DNA on ice for 15 min followed by drug for 1h) in 3'' processing of postasse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056891(2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mn+2, and DNA on ice for 15 min followed by drug for 1h) in strand transfer of postass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056891(2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mg+2, and drug for 30 min followed by DNA for 1h) in 3''-processing of preassembleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056891(2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...)
Affinity DataIC50:  700nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mn+2, and drug for 30 min followed by DNA for 1h) in strand transfer of preassembleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056891(2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mn+2, and DNA on ice for 15 min followed by drug for 1h) in 3'' processing of postasse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056891(2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mg+2, and DNA on ice for 15 min followed by drug for 1h) in strand transfer of postass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056891(2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mn+2, and drug for 30 min followed by DNA for 1h) in 3''-processing of preassembleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056891(2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...)
Affinity DataIC50:  700nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50056891(2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...)
Affinity DataIC50: >3.33E+5nMAssay Description:Inhibition of recombinant HIV1 integrase-mediated 3'-processing activity in presence of magnesiumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50056891(2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity in presence of manganeseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50056891(2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...)
Affinity DataIC50: >3.33E+5nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetT cell receptor alpha variable 4(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50056891(2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...)
Affinity DataIC50: >9.39E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay