BDBM50058046 CHEMBL526::propofol

SMILES CC(C)c1cccc(C(C)C)c1O

InChI Key InChIKey=OLBCVFGFOZPWHH-UHFFFAOYSA-N

Data  2 KI  5 IC50  8 EC50

PDB links: 8 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50058046   

TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50058046(CHEMBL526 | propofol)
Affinity DataIC50:  5.20E+4nMAssay Description:Inhibitory concentration against fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50058046(CHEMBL526 | propofol)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Organon Research And Development Group

Curated by ChEMBL
LigandPNGBDBM50058046(CHEMBL526 | propofol)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of [3H]azietomidate labelling of GABAA alpha1beta3gamma2L (unknown origin) expressed in Xenopus laevis oocytes assessed as reduction in ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Organon Research And Development Group

Curated by ChEMBL
LigandPNGBDBM50058046(CHEMBL526 | propofol)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of [3H]R-mTFD-MPAB labelling of GABAA alpha1beta3gamma2L (unknown origin) expressed in Xenopus laevis oocytes assessed as reduction in pho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Organon Research And Development Group

Curated by ChEMBL
LigandPNGBDBM50058046(CHEMBL526 | propofol)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of [3H]pTFD-di-iPr-BnOH labelling of GABAA alpha1beta3gamma2L (unknown origin) expressed in Xenopus laevis oocytes assessed as reduction i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed