BDBM50081174 CHEMBL3421968

SMILES COc1cc(ccc1Nc1nccc(n1)-c1cn(C)c2cnccc12)N1CCN(C)CC1

InChI Key InChIKey=ZYVXTMKTGDARKR-UHFFFAOYSA-N

Data  2 KI  25 IC50  3 Kd

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50081174   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Ach£

Curated by ChEMBL

LigandBDBM50081174(CHEMBL3421968)Copy SMILESCopy InChI

Affinity DataKi:  4.40nMAssay Description:Inhibition of human DYRK1A incubated for 90 mins in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMCE
PC cidPC sidPDBSimilars

In DepthDetails PubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£

Curated by ChEMBL

LigandBDBM50081174(CHEMBL3421968)Copy SMILESCopy InChI

Affinity DataKi:  11nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMCE
PC cidPC sidPDBSimilars

In DepthDetails PubMedPDB3D Structure (crystal)
Copy BDB DOI