BDBM50082665 4-(dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide::4-Dimethylamino-N-(6-hydroxycarbamoyl-hexyl)-benzamide::CHEMBL140000::US10188756, Compound CN52

SMILES CN(C)c1ccc(cc1)C(=O)NCCCCCCC(=O)NO

InChI Key InChIKey=MXWDSZWTBOCWBK-UHFFFAOYSA-N

Data  17 IC50

PDB links: 17 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50082665   

TargetLeukotriene A-4 hydrolase(Mus musculus)
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50082665(4-(dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50:  790nMAssay Description:Inhibition of LTA4H in C57BL/6 mouse assessed as reduction in LTB4 production pre-incubated for 30 mins before 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50082665(4-(dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50:  680nMAssay Description:Inhibition of recombinant human LTA4H Epoxide Hydrolase expressed in Escherichia coli BL21 (DE3) pLysS preincubated for 10 mins followed by addition ...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50082665(4-(dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50:  300nMAssay Description:Inhibition of recombinant human LTA4H aminopeptidase activity expressed in Escherichia coli BL21 (DE3) pLysS assessed as formation of p-NA from Ala-p...More data for this Ligand-Target Pair