BDBM50089005 (S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amino]-3-[4-(2,6-dichloro-benzyloxy)-phenyl]-propionic acid::2-[((4S,5S)-3-Acetyl-thiazolidine-4-carbonyl)-amino]-3-[4-(2,6-dichloro-benzyloxy)-phenyl]-propionic acid::CHEMBL351547
SMILES CC(=O)N1CSC[C@@H]1C(=O)N[C@@H](Cc1ccc(OCc2c(Cl)cccc2Cl)cc1)C(O)=O
InChI Key InChIKey=YBKFCWABWAQJTN-VQTJNVASSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50089005
Affinity DataIC50: 190nMAssay Description:Inhibition of alpha4-beta7 integrin mediated cell adhesionMore data for this Ligand-Target Pair
Affinity DataIC50: >8.00E+5nMAssay Description:Inhibition of alpha5-beta1 integrin mediated cell adhesionMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+5nMAssay Description:Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAMMore data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:In vitro inhibition of binding of integrin alpha4-beta1 to immobilized VCAM-1 expressed on endothelial cell surface.More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAMMore data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of CS-1 peptide binding to VLA-4 expressed in Ramos cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >8.00E+5nMAssay Description:Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAM by ELISA assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Celltech Chiroscience
Curated by ChEMBL
Celltech Chiroscience
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAMMore data for this Ligand-Target Pair