BDBM50095536 CHEMBL3590527::US9598381, 1 (racemate)

SMILES O[C@H](CNCCN(C1CCCCC1)C(=O)CCNCCc1ccc(Cl)c(Cl)c1)c1cccc2NC(=O)COc12

InChI Key InChIKey=BQLQGMSDFYMSGG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50095536   

TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM50095536(CHEMBL3590527 | US9598381, 1 (racemate))
Affinity DataIC50:  65nMAssay Description:Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM50095536(CHEMBL3590527 | US9598381, 1 (racemate))
Affinity DataIC50:  5.60nMAssay Description:Inhibition of SMYD2 (unknown origin) using biotinylated GSRAHSSHLKSKKGQSTSRH as substrate assessed as incorporation of tritium labeled methyl group f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed