Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'N-lysine methyltransferase SMYD2' and Ligand = 'BDBM50095536'
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095536(CHEMBL3590527 | US9598381, 1 (racemate))
Affinity DataIC50:  5.60nMAssay Description:Inhibition of SMYD2 (unknown origin) using biotinylated GSRAHSSHLKSKKGQSTSRH as substrate assessed as incorporation of tritium labeled methyl group f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095536(CHEMBL3590527 | US9598381, 1 (racemate))
Affinity DataIC50:  65nMAssay Description:Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To...More data for this Ligand-Target Pair
In DepthDetails US Patent