BDBM50097135 CHEMBL3580974

SMILES Clc1c(CNc2nccc(Nc3cc([nH]n3)C3CC3)n2)ccc2[nH]cnc12

InChI Key InChIKey=DYLHVDVCWIEYSA-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50097135   

TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner

Curated by ChEMBL
LigandPNGBDBM50097135(CHEMBL3580974)
Affinity DataKi:  5nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate assessed as substrate phosphorylation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Shanghai Chempartner

Curated by ChEMBL
LigandPNGBDBM50097135(CHEMBL3580974)
Affinity DataKi:  455nMAssay Description:Inhibition of human recombinant PAK4 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate assessed as substrate phosphorylation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner

Curated by ChEMBL
LigandPNGBDBM50097135(CHEMBL3580974)
Affinity DataIC50:  362nMAssay Description:Inhibition of PAK1 in human EBC1 cells assessed as inhibition of MEK phosphorylation at S298 after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed