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Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PAK 1' and Ligand = 'BDBM50097135'
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner

Curated by ChEMBL
LigandPNGBDBM50097135(CHEMBL3580974)
Affinity DataKi:  5nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate assessed as substrate phosphorylation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner

Curated by ChEMBL
LigandPNGBDBM50097135(CHEMBL3580974)
Affinity DataIC50:  362nMAssay Description:Inhibition of PAK1 in human EBC1 cells assessed as inhibition of MEK phosphorylation at S298 after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed