BDBM50107990 CHEMBL359144::xv5-Methyl-6-(pyren-1-ylaminomethyl)-pyrido[2,3-d]pyrimidineamine

SMILES Cc1c(CNc2ccc3ccc4cccc5ccc2c3c45)cnc2nc(N)nc(N)c12

InChI Key InChIKey=ZXPLJUACCJOOLA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107990   

TargetDihydrofolate reductase(Homo sapiens (Human))
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50107990(CHEMBL359144 | xv5-Methyl-6-(pyren-1-ylaminomethyl...)
Affinity DataIC50:  0.880nMAssay Description:Antimycobacterial activity against Mycobacterium avium complex diihydrofolate reductase (MAC DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50107990(CHEMBL359144 | xv5-Methyl-6-(pyren-1-ylaminomethyl...)
Affinity DataIC50:  3.80nMAssay Description:Antimycobacterial activity against human dihydrofolate reductase (hDHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed