BDBM50109702 CHEMBL3604174

SMILES Clc1ccc(NC(=O)c2cn[nH]n2)c(Cl)c1

InChI Key InChIKey=GAGGCNZJYKWGJL-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50109702   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109702(CHEMBL3604174)
Affinity DataIC50:  78nMAssay Description:Inhibition of pig 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arach...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109702(CHEMBL3604174)
Affinity DataIC50:  2.16E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109702(CHEMBL3604174)
Affinity DataIC50:  500nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109702(CHEMBL3604174)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109702(CHEMBL3604174)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of rat 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arach...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109702(CHEMBL3604174)
Affinity DataIC50:  5.81E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109702(CHEMBL3604174)
Affinity DataIC50:  99nMAssay Description:Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109702(CHEMBL3604174)
Affinity DataIC50:  56nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109702(CHEMBL3604174)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed