BDBM50121900 Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pro-Val-NH2::CHEMBL439490
SMILES CCCC[C@H](NC(=O)C(CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C(C)C)C(N)=O
InChI Key InChIKey=UAHFGYDRQSXQEB-BVMGHOOCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 20 hits for monomerid = 50121900
Affinity DataKi: 0.560nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R F184L expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.570nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R Y268F expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.630nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R I129A expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.630nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R F184A expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.630nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R I291A expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.820nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human wild type MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.970nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R Y287F expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R I125A expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R Y268A expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R Y287A expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Agonist activity at the mutant MC4R I125A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at the mutant MC4R Y287F expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 9nMAssay Description:Agonist activity at the mutant MC4R Y287A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Agonist activity at the mutant MC4R F184L expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20nMAssay Description:Agonist activity at the human wild type MC4R expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Agonist activity at the mutant MC4R Y268A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Agonist activity at the mutant MC4R Y268F expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 5.10nMAssay Description:Agonist activity at the mutant MC4R I291A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Agonist activity at the mutant MC4R I129A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 0.510nMAssay Description:Agonist activity at the mutant MC4R F184A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair