BDBM50122002 CHEMBL1383671

SMILES Nc1cnccc1C(O)=O

InChI Key InChIKey=FYEQKMAVRYRMBL-UHFFFAOYSA-N

Data  14 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50122002   

TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50122002(CHEMBL1383671)
Affinity DataIC50:  631nMAssay Description:Inhibition of KDM4C (unknown origin) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectrometric analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50122002(CHEMBL1383671)
Affinity DataIC50:  6.31E+4nMAssay Description:Inhibition of human KDM6B catalytic domain using H3(20 to 36 residues)K27Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4D(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50122002(CHEMBL1383671)
Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of human KDM4D (11 to 341 residues) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectromet...More data for this Ligand-Target Pair
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50122002(CHEMBL1383671)
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of full length His-MBP-att-EGLN3 (1 to 239 residues) (unknown origin) in Escherichia coli BL21(DE3)pRR692 cells assessed as hydroxylation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed