BDBM50123449 CHEMBL437996::Chloropeptin II::ISOCOMPLESTATIN
SMILES [H][C@@]12NC(=O)[C@H](NC(=O)[C@@H](Cc3c[nH]c4cc(ccc34)-c3cc1cc(Oc1ccc(C[C@H](N(C)C(=O)[C@H](NC2=O)c2cc(Cl)c(O)c(Cl)c2)C(=O)N[C@@H](C(O)=O)c2ccc(O)cc2)cc1)c3O)NC(=O)C(=O)c1cc(Cl)c(O)c(Cl)c1)c1cc(Cl)c(O)c(Cl)c1
InChI Key InChIKey=JJGZGELTZPACID-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50123449
TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against CD4-gp120 binding in the absence of fetal bovine serum (FBS); Range is 0.13-0.5 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of disintegration activity of HIV1 intact integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of integration activity of HIV1 intact integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of disintegration activity of HIV1 integrase catalytic core domain (50 to 212)More data for this Ligand-Target Pair