BDBM50129575 2,5-Dihydroxy-3-(1H-indol-3-yl)-[1,4]benzoquinone::CHEMBL312892

SMILES O=C1CC(=O)C(=O)C(c2c[nH]c3ccccc23)C1=O

InChI Key InChIKey=QMYWIHTZQCCLAU-UHFFFAOYSA-N

Data  1 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50129575   

TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50129575(2,5-Dihydroxy-3-(1H-indol-3-yl)-[1,4]benzoquinone ...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibitory constant of compound against Cdc25B phosphatase was determined using mFP as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50129575(2,5-Dihydroxy-3-(1H-indol-3-yl)-[1,4]benzoquinone ...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibitory concentration of compound against mutant E474Q of Cdc25B phosphatase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50129575(2,5-Dihydroxy-3-(1H-indol-3-yl)-[1,4]benzoquinone ...)
Affinity DataIC50:  7.60E+4nMAssay Description:Inhibitory concentration of compound against mutant F475A of Cdc25B phosphatase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50129575(2,5-Dihydroxy-3-(1H-indol-3-yl)-[1,4]benzoquinone ...)
Affinity DataIC50:  7.30E+4nMAssay Description:Inhibitory concentration of compound against mutant R482L of Cdc25B phosphatase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50129575(2,5-Dihydroxy-3-(1H-indol-3-yl)-[1,4]benzoquinone ...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibitory concentration of compound against mutant WT of Cdc25B phosphatase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50129575(2,5-Dihydroxy-3-(1H-indol-3-yl)-[1,4]benzoquinone ...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory concentration of compound against Cdc25B phosphatase was determined using CDK2-p-TpY/Cyclin A as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 3(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50129575(2,5-Dihydroxy-3-(1H-indol-3-yl)-[1,4]benzoquinone ...)
Affinity DataIC50:  3.00E+4nMAssay Description:Eight point inhibitory concentration against Cell division cycle 25 degree C was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50129575(2,5-Dihydroxy-3-(1H-indol-3-yl)-[1,4]benzoquinone ...)
Affinity DataIC50:  2.50E+4nMAssay Description:Eight point inhibitory concentration against Cell division cycle 25A was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50129575(2,5-Dihydroxy-3-(1H-indol-3-yl)-[1,4]benzoquinone ...)
Affinity DataIC50:  1.80E+4nMAssay Description:Eight point inhibitory concentration against Cell division cycle 25B was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50129575(2,5-Dihydroxy-3-(1H-indol-3-yl)-[1,4]benzoquinone ...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibitory concentration of compound against truncated mutant of Cdc25B phosphatase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed