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Found 8 Enz. Inhib. hit(s) with Target = 'M-phase inducer phosphatase 2' and Ligand = 'BDBM50129575'
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50129575(2,5-Dihydroxy-3-(1H-indol-3-yl)-[1,4]benzoquinone ...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibitory constant of compound against Cdc25B phosphatase was determined using mFP as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50129575(2,5-Dihydroxy-3-(1H-indol-3-yl)-[1,4]benzoquinone ...)
Affinity DataIC50:  1.80E+4nMAssay Description:Eight point inhibitory concentration against Cell division cycle 25B was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50129575(2,5-Dihydroxy-3-(1H-indol-3-yl)-[1,4]benzoquinone ...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibitory concentration of compound against mutant WT of Cdc25B phosphatase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50129575(2,5-Dihydroxy-3-(1H-indol-3-yl)-[1,4]benzoquinone ...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibitory concentration of compound against truncated mutant of Cdc25B phosphatase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50129575(2,5-Dihydroxy-3-(1H-indol-3-yl)-[1,4]benzoquinone ...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory concentration of compound against Cdc25B phosphatase was determined using CDK2-p-TpY/Cyclin A as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50129575(2,5-Dihydroxy-3-(1H-indol-3-yl)-[1,4]benzoquinone ...)
Affinity DataIC50:  7.30E+4nMAssay Description:Inhibitory concentration of compound against mutant R482L of Cdc25B phosphatase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50129575(2,5-Dihydroxy-3-(1H-indol-3-yl)-[1,4]benzoquinone ...)
Affinity DataIC50:  7.60E+4nMAssay Description:Inhibitory concentration of compound against mutant F475A of Cdc25B phosphatase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50129575(2,5-Dihydroxy-3-(1H-indol-3-yl)-[1,4]benzoquinone ...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibitory concentration of compound against mutant E474Q of Cdc25B phosphatase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed