BDBM50178769 (+/-)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide::6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide::CHEMBL420311
SMILES NC(=O)C1CCCc2c1[nH]c1ccc(Cl)cc21
InChI Key InChIKey=FUZYTVDVLBBXDL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50178769
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant SIRT2 using ZMAL substrate after 4 hrs by homogeneous fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant SIRT1 using ZMAL substrate after 4 hrs by homogeneous fluorescence assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of recombinant SIRT3 using ZMAL substrate after 4 hrs by homogeneous fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Inhibition of human SIRT1 deacetylase activity using acetylated H3K9 as substrate preincubated for 15 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged/SUMO-fused SIRT2 (38 to 356 residues) expressed in Escherichia coli BL21 assessed as reduction...More data for this Ligand-Target Pair