BDBM50178769 (+/-)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide::6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide::CHEMBL420311

SMILES NC(=O)C1CCCc2c1[nH]c1ccc(Cl)cc21

InChI Key InChIKey=FUZYTVDVLBBXDL-UHFFFAOYSA-N

Data  1 KI  53 IC50

PDB links: 6 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50178769   

TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Cemm-Research Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50178769((+/-)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-c...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human recombinant GST-tagged SIRT1 expressed in 293T cells by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cemm-Research Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50178769((+/-)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-c...)
Affinity DataIC50:  1.96E+4nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair