BDBM50188735 1-(3,5-dichlorophenyl)-3-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)thiophen-2-yl)methyl)urea::CHEMBL380397

SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3ccc(CNC(=O)Nc4cc(Cl)cc(Cl)c4)s3)c2)CC1

InChI Key InChIKey=QFUMXJTWUNRHSU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50188735   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188735(1-(3,5-dichlorophenyl)-3-((5-(6-((4-methylpiperazi...)
Affinity DataIC50:  79nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188735(1-(3,5-dichlorophenyl)-3-((5-(6-((4-methylpiperazi...)
Affinity DataIC50:  38nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188735(1-(3,5-dichlorophenyl)-3-((5-(6-((4-methylpiperazi...)
Affinity DataIC50:  2.28E+3nMAssay Description:Inhibition of FLT1 at 1mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed