BDBM50194042 5-4-2,5-dichlorophenoxy)phenylamino)-3-hydroxy-N-2-4-methylpiperazin-1-yl)ethyl)isothiazole-4-carboximidamide::CHEMBL214977

SMILES CN1CCN(CCN=C(N)c2c(Nc3ccc(Oc4cc(Cl)ccc4Cl)cc3)s[nH]c2=O)CC1

InChI Key InChIKey=JZLYYEVDXWGIGL-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50194042   

TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194042(5-4-2,5-dichlorophenoxy)phenylamino)-3-hydroxy-N-2...)
Affinity DataEC50:  118nMAssay Description:Inhibitory activity against MEK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194042(5-4-2,5-dichlorophenoxy)phenylamino)-3-hydroxy-N-2...)
Affinity DataIC50:  137nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed