BDBM50239433 CHEMBL3134585

SMILES FC(F)(F)C(=O)Nc1sc2CCCCCc2c1C(=O)Nc1ccccc1

InChI Key InChIKey=PRBJMPPJVJEDLT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50239433   

TargetAnoctamin-1(Homo sapiens (Human))
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239433(CHEMBL3134585)
Affinity DataIC50:  130nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 5 mins followed by A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239433(CHEMBL3134585)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human TMEM16B expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-1(Homo sapiens (Human))
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239433(CHEMBL3134585)
Affinity DataIC50:  300nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed