BDBM50239464 CHEMBL4085154

SMILES Cc1ccccc1NC(=O)c1c(NC(=O)C(F)(F)I)sc2CCCCCc12

InChI Key InChIKey=LJHWIWGPTSSLEA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50239464   

TargetAnoctamin-1(Homo sapiens (Human))
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239464(CHEMBL4085154)
Affinity DataIC50:  730nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 5 mins followed by A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-1(Homo sapiens (Human))
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239464(CHEMBL4085154)
Affinity DataIC50:  600nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239464(CHEMBL4085154)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human TMEM16B expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed