BDBM50239467 CHEMBL4086165

SMILES COc1cc(Nc2ccc(cc2C(O)=O)[N+]([O-])=O)cc2ccccc12

InChI Key InChIKey=JIVRLHBAUUZTNC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50239467   

TargetAnoctamin-1(Homo sapiens (Human))
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239467(CHEMBL4086165)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 5 mins followed by A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239467(CHEMBL4086165)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human TMEM16B expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-1(Homo sapiens (Human))
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239467(CHEMBL4086165)
Affinity DataIC50:  80nMAssay Description:Inhibition of TMEM16A (unknown origin) expressed in Xenopus laevis oocytes at -60 mV holding potential by voltage-clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed